AMBROXOL AND DESLORATIDINE IN BULK AND PHARMACEUTICAL DOSAGE FORM

Ngatidjan

Volume 14, Issue 03 2024

Abstract:

Excessive salt consumption is one of the hypertension and kidney disease factors, while telmisartan is one of antihypertensive drugs used in the therapy. Telmisartan not only blocks angiotensin receptor which leads to the decrease of blood pressure, but also activates peroxisome proliferator activated receptor gamma (PPAR-γ) and inhibits transforming growth expression factor of beta-1 (TGFβ-1). Whether telmisartan decreases the kidney collagen volume fraction of excessive NaCl–induced Wistar rats are studied in this experiment.

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